Conference Proceedings

              SPIE Future Sensing Technologies | (2020) | Publications | Spie.        OSA 100 Years

  1. H.K. Kim, A. Raghuram, Y. Zhao, A. Veeraraghavan, J. Robinson, and A.H. Hielscher, “Ultrahigh spatiotemporal resolution fluorescence molecular tomography with a sparsity constrained dimensional reduction reconstruction model,” in Proc. SPIE 11971: High-Speed Biomedical Imaging and Spectroscopy VII, San Francisco, CA, January 22-27, 2022. [11971-0A]
  2. M.L Altoe, A. Marone, H.K. Kim, M. Tejada, H. Hibshoosh, H. Guo, K. Crew, M. Accordino, M. Trivedi K. Kalinsky, D. Hershman, and A.H. Hielscher, “Early treatment window for predicting breast cancer response to neoadjuvant chemotherapy in the HR+/HER2-subgroup using diffuse optical tomography,” in Proc. SPIE 11944: Multiscale Imaging and Spectroscopy III, San Francisco, CA, January 22-27, 2022. [11944-03]
  3. A. Marone, N. Maheshwari, H.K. Kim, D.R. Bajakian, and A.H. Hielscher, “Initial evaluation of the use of dynamic vascular optical imaging for predicting outcome of surgical intervention to improve blood perfusion in feet of diabetic patients,” in Proc. SPIE 11968: Optical Diagnostics and Sensing XXII: Toward Point-of-Care Diagnostics, San Francisco, CA, January 22-27, 2022. [11968-09]
  4. N. Maheshwari, A. Marone, M. Altoe, H.K. Kim, D.R. Bajakian, and A.H. Hielscher, “Pilot study on monitoring ulcer healing with diffuse optical imaging in a patient cohort affected by peripheral arterial disease (PAD),” in Proc. SPIE 11968: Optical Diagnostics and Sensing XXII: Toward Point-of-Care Diagnostics, San Francisco, CA, January 22-27, 2022. [11968-0A]
  5. F. Wang, A.H. Hielscher, and S.K. Kim, “Employing a neural network approach for reducing the convergence speed of diffuse optical image reconstruction algorithms,” in Proc. SPIE 11971: High-Speed Biomedical Imaging and Spectroscopy VII, San Francisco, CA, January 22-27, 2022. [11971-09] 
  6. S. Ghosh, M.L. Altoe, A. Marone, H.K. Kim, K. Kalinsky, H. Guo, H. Hibshoosh, M. Tejada, K. Crew, M.K. Accordino, M. Trivedi, D. Hershman, and A.H. Hielscher, “Prediction of pathologic complete response in breast cancer neoadjuvant chemotherapy based on pretreatment data obtained with dynamic diffuse optical tomography,” in Proc. SPIE 11944: Multiscale Imaging and Spectroscopy III, San Francisco, CA, January 22-27, 2022. [11944-02]
  7. M.L. Altoe, A. Marone, H.K. Kim, H. Guo, H. Hibshoosh, M. Tejada, K. Crew, M. Accordino, M. Trivedi, K. Kalinsky, D. Hershman, and A.H. Hielscher, “Total hemoglobin changes in the breast tumors volume of patients undergoing neoadjuvant chemotherapy: a longitudinal analysis,” in Proc. SPIE 11639: Optical Tomography and Spectroscopy of Tissue XIV, Virtual, March 6-11, 2021. [11639-09]
  8. A. Marone, M. Smith, N. Maheshwari, H.K. Kim, D.R. Bajakian, and A.H. Hielscher, “Vascular optical spectroscopy for the detection of contrast-agent perfusion during x-ray angiography in peripheral artery disease patients undergoing a surgical intervention,” in Proc. SPIE 11639: Optical Tomography and Spectroscopy of Tissue XIV, Virtual, March 6-11, 2021. [11639-0G]
  9. M.L. Altoe, J.W. Hoi, C.J. Fong, Y. Kim, H.K. Kim, D.R. Bajakian, A.H. Hielscher, “Diffuse optical tomography provides a biomarker for breast cancer risk that is modifiable by neoadjuvant chemotherapy,” in Proceedings of the 2020 ARRS Annual Meeting, Chicago, IL, May 3 – 8, 2020.
  10. A. Marone, J.W. Hoi, C.J. Fong, Y. Kim, H.K. Kim, D.R. Bajakian, A.H. Hielscher, “Using dynamic vascular optical spectroscopy to evaluate peripheral arterial disease (PAD) in patients who undergo a vascular intervention,” in Proc. SPIE 10874: Optical Tomography and Spectroscopy of Tissue XIII, S. Fantini, ed., San Francisco, CA, Feb. 2-7, 2019. [10874-14]
  11. A. Marone, Y. Kim, G. Danias, K.E. Neville, A.T. Frantz, T.M. Kapoor, L.Geraldino-Pardilla, A.D. Askanase, A.H. Hielscher, “A new method based on frequency-domain optical tomography to diagnose joints affected by systemic lupus erythematosus,” in Proc. SPIE 10874: Optical Tomography and Spectroscopy of Tissue XIII, S. Fantini, ed., San Francisco, CA, February 2 – 7, 2019. [10874-15]
  12. K. Kim, J.H. Lee, D. Kim, A.H. Hielscher, “Spatial-temporal constraints guided dynamic fluorescence tomographic model for enhanced imaging of organs and functional structures in small animals,” in Proc. SPIE 10874: Optical Tomography and Spectroscopy of Tissue XIII, S. Fantini, ed., San Francisco, CA, February 2 – 7, 2019. [10874-76]
  13. L. Altoe, A. Marone, H.K. Kim, M. Tejada, H. Hibshoosh, K. Crew, K. Kalinsky, D.L. Hershman, A.H. Hielscher, “Monitoring total hemoglobin concentration changes across neoadjuvant chemotherapy in HER2-positive and HER2-negative breast cancer with diffuse optical tomography,” in Proc. SPIE 10874: Optical Tomography and Spectroscopy of Tissue XIII, S. Fantini, ed., San Francisco, CA, February 2 – 7, 2019. [10874-57]
  14. Kim, A. Marone, G. Danias, K.E. Neville, A.T. Frantz, T. Kapoor, L. Geraldino-Pardilla, I. Kymissis, Anca D. Askanase, A.H. Hielscher, “Flexible optical imaging bands for the assessment of systemic Lupus erythematosus in finger joints,” in Proc. SPIE 10885: Optical Diagnostics and Sensing XIX: Toward Point-of-Care Diagnostics, G.L. Coté, ed., San Francisco, CA, February 2 – 7, 2019. [10885-37]
  15. L. Altoe, J.E. Gunther, E. Lim, H.K Kim, J. Campbell, H. Hibshoosh, K. Crew, K. Kalinsky, D.L. Hershman, A.H. Hielscher, “Baseline oxygen saturation comparison between pathologic complete responders and extensive residual cancer cases in response to neoadjuvant chemotherapy,” in Proc. SPIE 10059, Optical Tomography and Spectroscopy of Tissue XII, B.J. Tromberg, A.G. Yodh, E.M. Sevick Muraca, R.R. Alfano, eds. 100590Q (17 February 2017); doi: 10.1117/12.2251452.
  16. W. Hoi, H.K. Kim, A.H. Hielscher, “A Non-Contact Fiber-Less Diffuse Optical Tomographic System for Dynamic Imaging of the Feet with Peripheral Artery Disease,” Biomedical Optics Congress, Ft. Lauderdale, FL, OSA Technical Digest (online) (Optical Society of America, 2016), paper JW3A.15, doi:10.1364/CANCER.2016.JW3A.15
  17. Marone1, J.W. Hoi, M. Khalil, H. Kim, R. Dayal, G. Shrikhande, A.H. Hielscher, “Effects of Posture and Heart Rate Changes on Optical Tomographic Imaging of the Peripheral Arteries,” Biomedical Optics Congress, Ft. Lauderdale, FL, OSA Technical Digest (online) (Optical Society of America, 2016), paper OTh2C.5, doi:10.1364/OTS.2016.OTh2C.5
  18. H. Lee, H.K. Kim, E. Lim, A.H. Hielscher, “Development of a Rotatable Optical Probe for Trans-rectal Ultrasound Coupled Diffuse Optical Tomography imaging of Prostate Cancer,” Biomedical Optics Congress, Ft. Lauderdale, FL, OSA Technical Digest (online) (Optical Society of America, 2016), paper JM3A.5 doi:10.1364/CANCER.2016.JM3A.5
  19. E. Gunther, E. Lim1, H.K. Kim, M. Altoe, S. Refrice, M. Brown, K. Kalinsky, D.L. Hershman, A.H. Hielscher, “5-Month Monitoring of Tumor Response in Patients with Breast Cancer who undergo Neoadjuvent Therapy with Diffuse Optical Tomography,” Biomedical Optics Congress, Ft. Lauderdale, FL, OSA Technical Digest (online) (Optical Society of America, 2016), paper JM4A.2 •doi:10.1364/CANCER.2016.JM4A.2
  20. K. Kim, N. Tucker, F. Debernardis, A.H. Hielscher, “Melanoma Detection and Characterization with a 6-layered multispectral model,“ Biomedical Optics Congress, Ft. Lauderdale, FL, OSA Technical Digest (online) (Optical Society of America, 2016), paper JTu3A.26 •doi:10.1364/CANCER.2016.JTu3A.26
  21. E. Gunther, E. Lim, H.K. Kim, M.L. Flexman, L. Zweck, S. Arora, S. Refice, M. Brown, K. Kalinsky, D.L. Hershman, A.H. Hielscher, “Combined dynamic and static optical tomography for prediction of treatment outcome in breast cancer patients,” Proc. SPIE 9538, Diffuse Optical Imaging V, H. Dehghani, P. Taroni, eds., 953811 (16 July 2015); doi: 10.1117/12.2183996
  22. Marone, J.W. Hoi, M.A. Khalil, H.-K.Kim, G. Shrikhande, R. Dayal, A.H. Hielscher, “Modeling of the blood flow in the lower extremities for dynamic diffuse optical tomography of peripheral artery disease,” Proc. SPIE 9538, Diffuse Optical Imaging V, H. Dehghani, P. Taroni, eds., 95380Z (16 July 2015). (doi: 10.1117/12.2183948)
  23. J. Fong, J.W. Hoi, H.K. Kim, G. Behr, L. Geller, N. Antonov, M. Flexman; M. Garzon, A.H. Hielscher, “Characterizing infantile hemangiomas with near-infrared spectroscopic handheld wireless device,”  in Proc. SPIE. 9319: Optical Tomography and Spectroscopy of Tissue XI, B.J. Tromberg, A.G. Yodh, E.M. Sevick-Muraca, R.R. Alfano, eds., 931920, 2015. (doi: 10.1117/12.2079710)
  24. K. Kim, J.E. Gunther, J.W. Hoi, A.H. Hielscher, “A reduced-space basis function neural network method for diffuse optical tomography,” in Proc. SPIE. 9319: Optical Tomography and Spectroscopy of Tissue XI, B.J. Tromberg, A.G. Yodh, E.M. Sevick-Muraca, R.R. Alfano, eds., 931925, 2015 (doi: 10.1117/12.2080550)
  25. W. Hoi, H.K. Kim, M.A. Khalil, C.J. Fong, A. Marone, G. Shrikhande, A.H. Hielscher, “Non-contact continuous-wave diffuse optical tomography system to capture vascular dynamics in foot,” Proc. SPIE 9313: Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XIII, A. Mahadevan-Jansen; T. Vo-Dinh, W.S. Grundfest, Q. Liu, eds., 931312, 2015. (doi:10.1117/12.2080184)
  26. E. Gunther, E. Lim, H.K. Kim, M. Brown, S. Refice, L. Zweck, M.L. Flexman, K.Kalinsky, D. Hershman, A.H. Hielscher, Dynamic diffuse optical tomography for assessing changes of breast tumors during neoadjuvant chemotherapy,” in Proc. SPIE 9319: Optical Tomography and Spectroscopy of Tissue XI, B.J. Tromberg, A.G. Yodh, E.M. Sevick-Muraca, R.R. Alfano, eds., 93190C, 2015. (doi:10.1117/12.2079435)
  27. E. Gunther, E. Lim, H.K. Kim, M. Flexman, M. Brown, S. Refice, K. Kalinsky, Kevin, D. Hershman, A.H. Hielscher, “Predicting Tumor Response in Breast Cancer Patients Using Diffuse Optical Tomography,” Proceedings of European Conference on Biomedical Optics, Munich, Germany, May 12-16, 2013. (Best Student Paper Award)
  28. Khalil, H.K. Kim, M. Barbieri, I-K Kim, R. Dayal, G. Shrikhande, A. H. Hielscher, “Detection of poor blood circulation in the lower extremities using dynamic diffuse optical tomography,” Proceedings of European Conference on Biomedical Optics, Munich, Germany, May 12-16, 2013.
  29. K. Kim, M. Khalil, J. Gunther, L. Montejo, A.H. Hielscher, “A Dynamic Image Reconstruction Method with Spatio-Temporal Constraints,” In Photons Plus Ultrasound: Imaging and Sensing 2013, edited by Alexander A. Oraevsky, Lihong V. Wang, Proc. of SPIE Vol. 8581, Paper 858131 (2013). doi: 10.1117/12.2003394
  30. L.D. Montejo, J. Jia, H.K. Kim, A.H. Hielscher, “Evaluation of Fourier Transform Coefficients for The Diagnosis of Rheumatoid Arthritis From Diffuse Optical Tomography” Images,” in Optical Tomography and Spectroscopy of Tissue X, J. Tromberg, A.G. Yodh, E.M. Sevick-Muraca, Proceedings of SPIE Vol. 8578, Paper 8578-60 (2013).
  31. J. Fong, M. Flexman, J.W. Hoi, L.Geller, M. Garzon, H.K. Kim, A.H. Hielscher, “A Handheld Wireless Device for Diffuse Optical Spectroscopic Assessment of Infantile Hemangiomas,” in Optical Tomography and Spectroscopy of Tissue X, B.J. Tromberg, A.G. Yodh, E.M. Sevick-Muraca, Proceedings of SPIE Vol. 8578, Paper 8578-27 (2013).
  32. A. Khalil, J. Hoi, H. K. Kim, A. H. Hielscher, “Dynamic contact-free continuous-wave diffuse optical tomography system for the detection of vascular dynamics within the foot,” in Optical Tomography and Spectroscopy of Tissue X,  B.J. Tromberg, A.G. Yodh, E.M. Sevick-Muraca, Proceedings of SPIE Vol. 8578, Paper 8578-54 (2013).
  33. A. Khalil, H.K. Kim, J.W. Hoi, I. Kim, R. Dayal, G. Shrikhande, A. H. Hielscher, “Detection of poor perfusion in the foot using diffuse optical tomography, in Optical Tomography and Spectroscopy of Tissue X, B.J. Tromberg, A.G. Yodh, E.M. Sevick-Muraca, Proceedings of SPIE Vol. 8578, Paper 8578-59 (2013).
  34. H. Lee, H.K. Kim, J. Jia, C. Fong, A.H. Hielscher, “A fast full-body fluorescence/ bioluminescence imaging system for small animals, “in Optical Tomography and Spectroscopy of Tissue X, B.J. Tromberg, A.G. Yodh, E.M. Sevick-Muraca, Proceedings of SPIE Vol. 8578, Paper 8578-21 (2013).
  35. Jia, J.H. Lee, L.D. Montejo, H.K. Kim, A.H. Hielscher,” Measurement Operator for Angular Dependent Photons Propagation in Contact-Free Optical Tomography, in Optical Tomography and Spectroscopy of Tissue X, B.J. Tromberg, A.G. Yodh, E.M. Sevick-Muraca, Proceedings of SPIE Vol. 8578, Paper 8578-41 (2013).
  36. E. Gunther, E. Lim, H.K. Kim, M. Flexman, M. Brown4, S. Refrice, K. Kalinsky, D. Hershman, A.H. Hielscher, “Using Diffuse Optical Tomography to Monitor Tumor Response to Neoadjuvant Chemotherapy in Breast Cancer Patients,” in Optical Tomography and Spectroscopy of Tissue X,  edited by B.J. Tromberg, A.G. Yodh, E.M. Sevick-Muraca, Proc. of SPIE Vol. 8578, Paper 8578-19 (2013).
  37. Khalil, H.K. Kim, I.K. Kim, R. Dayal, A.H. Hielscher, “Detecting lower extremity vascular dynamics in patients with peripheral artery disease using diffuse optical tomography,” in Optical Tomography and Spectroscopy of Tissue IX, B.J. Tromberg, A.G Yodh, M. Tamura, E.M. Sevick-Muraca, R.R. Alfano, eds., Proceedings of SPIE Vol. 7896 [78962Z] (2011). DOI: 10.1117/12.874236
  38. L. Flexman, M. Khalil, R.M. Al Abdi, B. Reig, C.J. Fong, D.L. Hershman, E. Desperito, R.L. Barbour, A.H. Hielscher, “Optical tomographic imaging of the hemodynamic response to a breath hold in breast cancer patients,” in Optical Tomography and Spectroscopy of Tissue IX, B.J. Tromberg, A.G Yodh, M. Tamura, E.M. Sevick-Muraca, R.R. Alfano, eds., Proceedings of SPIE Vol. 7896 (2011). DOI: 10.1117/12.875461
  39. L. Flexman, H.K. Kim, S.L. Hernandez, J. Huang, T.J. Johung, J.H. Lee, F. Vlachos, D.J. Yamashiro, J. Kandel, A.H. Hielscher, “Optical tomographic monitoring of vascular responses to anti-angiogenic drugs in preclinical tumor models,” in Optical Tomography and Spectroscopy of Tissue IX, B.J. Tromberg, A.G Yodh, M. Tamura, E.M. Sevick-Muraca, R.R. Alfano, eds., Proceedings of SPIE Vol. 7896 [789627] (2011). DOI: 10.1117/12.875422
  40. D. Montejo, H.K. Kim, A.D. Klose, A.H. Hielscher, “A finite-volume algorithm for modeling light transport with the time-independent simplified spherical harmonics approximation to the equation of radiative transfer,” in Optical Tomography and Spectroscopy of Tissue IX, B.J. Tromberg, A.G Yodh, M. Tamura, E.M. Sevick-Muraca, R.R. Alfano, eds., Proceedings of SPIE Vol. 7896 [78960J] (2011). DOI: 10.1117/12.875967
  41. D. Montejo, J.D. Montejo, H.K. Kim, U.J. Netz, C.D. Klose, S. Blaschke, P.A. Zwaka, G.A. Müller, J. Beuthan, A.H. Hielscher, “Analysis and classification of optical tomographic images of rheumatoid fingers with ANOVA and discriminate analysis” in Optical Tomography and Spectroscopy of Tissue IX, A. Mahadeva-Jansen, T. Vo-Dinh, W.S. Grundfest, eds., Proceedings of SPIE Vol. 7890 [78900L] (2011). DOI: 10.1117/12.875977
  42. K. Kim, M. L. Flexman, D.J. Yamashiro, J.J. Kandel, A. H. Hielscher, “Transport-theory based multispectral imaging with PDE-constrained optimization,” in Advanced Biomedical and Clinical Diagnostic Systems IX, B.J. Tromberg, A.G Yodh, M. Tamura, E.M. Sevick-Muraca, R.R. Alfano, eds., Proceedings of SPIE Vol. 7896 [78960W] (2011). DOI: 10.1117/12.875908
  43. D. Klose, H.K. Kim, U.J. Netz, S. Blaschke, P.A. Zwaka, G.A. Müller, J. Beuthan, A.H. Hielscher, “Computer-aided classification of rheumatoid arthritis in finger joints using frequency domain optical tomography,” in Advanced Biomedical and Clinical Diagnostic Systems VII, A. Mahadevan-Jansen, T. Vo-Dinh, W.S. Grundfest, eds. SPIE International Symposium on Biomedical Optics Proc. 7169, paper [7169-39], 2009.
  44. D. Klose, A.D. Klose, U.J. Netz, J. Beuthan, A.H. Hielscher, “Optical tomographic detection of rheumatoid arthritis with computer-aided classification schemes,” in Multimodal Biomedical Imaging IV, F.S. Azar, X. Intes, eds., SPIE International Symposium on Biomedical Optics Proc. 7171, paper [7171‑11], 2009.
  45. M. Masciotti, J.H. Lee, M. Steward, A. H. Hielscher, “Instrumentation for simultaneous magnetic resonance and optical tomographic imaging of the rodent brain,” in Multimodal Biomedical Imaging IV, F.S. Azar, X. Intes, eds., SPIE International Symposium on Biomedical Optics Proc. 7171, paper [7171‑25], 2009.
  46. Gu, H.K. Kim, J.M. Masciotti, A.H. Hielscher, “A parallel reduced-space sequential-quadratic programming approach to small animal optical tomography,” in Optical Tomography and Spectroscopy of Tissue VIII, B.J. Tromberg, A.G. Yodh, M. Tamura, E.M. Sevick-Muraca, R.R. Alfano, eds., SPIE International Symposium on Biomedical Optics Proc. 7174, paper 717406 (11 pages), 2009.
  47. L. Flexman, J.M. Masciotti, M. Khalil, A. Ling, R.M. Al Abdi, R.L. Barbour, A.H. Hielscher, “Development of dynamic optical tomographic breast imaging system with digital detection techniques,” in Optical Tomography and Spectroscopy of Tissue VIII, B.J. Tromberg, A.G. Yodh, M. Tamura, E.M. Sevick-Muraca, R.R. Alfano, eds., SPIE International Symposium on Biomedical Optics Proc. 7174, paper [7174‑28], 2009. DOI: 10.1117/12.809153
  48. D. Montejo, A.D. Klose, A.H. Hielscher, “Implementation of a Block-Structured Grid for Modeling Fluorescence Light Propagation in Arbitrary Shaped Tissue,” in Optical Tomography and Spectroscopy of Tissue VIII, B.J. Tromberg, A.G. Yodh, M. Tamura, E.M. Sevick-Muraca, R.R. Alfano, eds., SPIE International Symposium on Biomedical Optics Proc. 7174, paper [7174‑40], 2009.
  49. K. Kim, X. Gu, A.H. Hielscher, “An all-at-once reduced Hessian SQP algorithm for frequency domain optical tomography,” in Optical Tomography and Spectroscopy of Tissue VIII, B.J. Tromberg, A.G. Yodh, M. Tamura, E.M. Sevick-Muraca, R.R. Alfano, eds., SPIE International Symposium on Biomedical Optics Proc. 7174, paper [7174‑79], 2009.
  50. K. Kim, U.J. Netz, J. Beuthan, A.H. Hielscher, “Optimal frequencies for small-tissue imaging based on the equation of radiative transfer,” in Optical Tomography and Spectroscopy of Tissue VIII, B.J. Tromberg, A.G. Yodh, M. Tamura, E.M. Sevick-Muraca, R.R. Alfano, eds., SPIE International Symposium on Biomedical Optics Proc. 7174, paper [7174‑81], 2009.
  51. L. Flexman, Y. Li, A.M. Bur, C.J.  Fong,  J.M. Masciotti, R. Al Abdi, R.L. Barbour, A.H. Hielscher, “The design and characterization of a digital optical breast cancer imaging system,” in Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS), pp. 3735-3738, August, 20-25 (2008).
  52. M. Masciotti, G.L. Franke, H.K. Kim, A.H. Hielscher, “Frequency Domain Optical Tomography Instrument with High Modulation Frequencies for Imaging Small Geometries,” Optical Society of America (OSA) Topical Meeting on Biomedical Optics, St. Petersburg, FL, March 16-20, 2008.
  53. D. Klose, H.K. Kim, A.H. Hielscher “Fluorescence Tomography with the Frequency Domain Equation of Radiative Transfer,” Optical Society of America (OSA) Topical Meeting on Biomedical Optics, St. Petersburg, FL, March 16-20, 2008.
  54. Li, A. M. Bur, C.J. Fong, M.L. Flexman, R.A. Abdi, R.L. Barbour, A.H. Hielscher, “Design of a Digital Optical Tomography System for Dynamic Breast Imaging,” Optical Society of America (OSA) Topical Meeting on Biomedical Optics, St. Petersburg, FL, March 16-20, 2008.
  55. D. Klose, A.D. Klose, A. Scheel, U. Netz, J. Beuthan, A.H. Hielscher,” Detecting Rheumatic Arthritis by Artificial Intelligent Multi-Parameter Classifications of Optical Tomographic Images,” Optical Society of America (OSA) Topical Meeting on Biomedical Optics, St. Petersburg, FL, March 16-20, 2008.
  56. K. Kim, J. Masciotti, A.H. Hielscher, “Transport Theory-Based Multi-Spectral Imaging of Tissue Chromophores Concentrations,” Optical Society of America (OSA) Topical Meeting on Biomedical Optics, St. Petersburg, FL, March 16-20, 2008.
  57. K. Kim, U.J. Netz, J. Beuthan, A.H. Hielscher, “Optimal Source-Modulation Frequencies for Small-Geometry Frequency-Domain Optical Tomography,” Optical Society of America (OSA) Topical Meeting on Biomedical Optics, St. Petersburg, FL, March 16-20, 2008.
  58. Gu, A.H. Hielscher, “Parallelization of Transport-Theory Based Optical Tomography Algorithms by Domain Decomposition,” Optical Society of America (OSA) Topical Meeting on Biomedical Optics, St. Petersburg, FL, March 16-20, 2008.
  59. Gu, A.H. Hielscher, “A PDE-Constrained Optimization Approach to Optical Tomography,” Optical Society of America (OSA) Topical Meeting on Biomedical Optics, St. Petersburg, FL, March 16-20, 2008.
  60. J. Netz, J. Beuthan, A.H. Hielscher, “Frequency-Domain Optical Imaging with GHz Multipixel Detection,” Optical Society of America (OSA) Topical Meeting on Biomedical Optics, St. Petersburg, FL, March 16-20 , 2008.
  61. H. Hielscher, Joseph M. Lasker, Chris J. Fong, Edward Dwyer, “Optical Tomographic Imaging of Hemodynamic Effects in Arthritic Joints,” Optical Society of America (OSA) Topical Meeting on Biomedical Optics, St. Petersburg, FL, March 16-20, 2008.
  62. D. Klose, A.D. Klose, U. Netz, A. Scheel, J. Beuthan, A.H. Hielscher, “Multi-Parameter Optical Image Interpretations Based on Self-Organizing Mapping,” in Multimodal Biomedical Imaging III, edited by Fred S. Azar, Xavier Intes, Proc. of SPIE Vol. 6850, 68500G-1 to 68500G-6 (2008).
  63. Minet, J. Beuthan, A.H. Hielscher, U. Zabarylo, “Optical monitoring of rheumatoid arthritis: Monte Carlo generated reconstruction kernels,” in Optical Technologies in Biophysics and Medicine IX, edited by Valery V. Tuchin, Proc. of SPIE Vol. 6791, 67910G (2008). DOI: 10.1117/12.803975.
  64. M. Lasker, J.M. Masciotti, Y. Li, C. Fong, A.H. Hielscher, “Dynamic optical tomographic imager with optimized digital lock-in filtering,” in Diffuse Optical Imaging of Tissue, edited by B.W. Pogue, R. Cubeddu, Proc. of SPIE-OSA Biomedical Optics, SPIE Vol. 6629, 662903-1 to 662903-11 (2007).
  65. H. Hielscher, J.M. Lasker, C.J. Fong, and Edward Dwyer, “Imaging of hemodynamic effects in arthritic joints with dynamic optical tomography,” in Diffuse Optical Imaging of Tissue, edited by B.W. Pogue, R. Cubeddu, Proc. of SPIE-OSA Biomedical Optics, SPIE Vol. 6629, 66290N-1 to 66290N-10 (2007).
  66. Gu, K. Ren, A.H. Hielscher, “Sensitivity analysis for small imaging domains using the frequency-domain transport equation,” in Diffuse Optical Imaging of Tissue, edited by B.W. Pogue, R. Cubeddu, Proc. of SPIE-OSA Biomedical Optics, SPIE Vol. 6629, 66291Q-1 to 66291Q-11 (2007).
  67. M. Masciotti, S. Rahim, J. Grover, A.H. Hielscher, “Design of a frequency-domain instrument for simultaneous optical tomography and magnetic resonance imaging of small animals,” in Multimodal Biomedical Imaging II, F.S. Azar, D.N. Metaxas, eds., SPIE International Symposium on Biomedical Optics, Proc. 6431, paper # 643113 (2007).
  68. K. Kim, A.H. Hielscher, “Comparison of spatial differencing schemes for the equation of radiative transfer applied to biomedical tissues,” in Optical Tomography and Spectroscopy of Tissue VII, B. Chance, R.R. Alfano, B.J. Tromberg, M Tamura, E.M. Sevick-Muraca, eds., SPIE International Symposium on Biomedical Optics, Proc. 6434, paper # 643424  (2007).
  69. Gu, K. Ren, J.M. Masciotti, A.H. Hielscher, “ Parametric image reconstruction using the discrete cosine transform for optical tomography,” in Optical Tomography and Spectroscopy of Tissue VI, B. Chance, R.R. Alfano, B.J. Tromberg, M Tamura, E.M. Sevick-Muraca, eds., SPIE International Symposium on Biomedical Optics, Proc. 6434, paper # 64342B (2007).
  70. M. Lasker, J. Masciotti, M. Schoenecker, C. Schmitz, A.H. Hielscher, “Digital Detection Techniques for Dynamic Optical Tomographic Imaging,” in Optical Tomography and Spectroscopy of Tissue VI, B. Chance, R.R. Alfano, B.J. Tromberg, M Tamura, E.M. Sevick-Muraca, eds., SPIE International Symposium on Biomedical Optics, Proc. 6434, paper # 64341T (2007).
  71. J. Netz, A.K. Scheel, J. Beuthan, A.H. Hielscher, “Development of a Finger Joint Phantom for Evaluation of Frequency Domain Measurement Systems,” 28th Annual International Conference of the IEEE – Engineering in Medicine and Biology Society, pp. 1937-1940 (2006)
  72. Gu, K. Ren, J.M. Masciotti, A.H. Hielscher, “Parametric Reconstruction Method in Optical Tomograhy,” 28th Annual International Conference of the IEEE – Engineering in Medicine and Biology Society, pp. 2667 – 2670 (2006).
  73. M. Masciotti, J.M. Lasker, A.H. Hielscher, “Digital Lock-in Algorithm for Biomedical Spectroscopy and Imaging Instruments with Multiple Modulated Sources,” 28th Annual International Conference of the IEEE – Engineering in Medicine and Biology Society, pp. 3198 – 3201 (2006)
  74. Song, A.D. Klose, A.K. Scheel, U. Netz, J. Beuthan, A.H. Hielscher, “Comparison of Two and Three-Dimensional Optical Tomographic Image Reconstructions of Human Finger Joints,” 28th Annual International Conference of the IEEE – Engineering in Medicine and Biology Society, pp. 6553 – 6556 (2006).
  75. M. Masciotti, F.A. Provenzano, J.C. Papa, J. Hur, X. Gu, Q. Wu, A.D. Klose, D. Yamashiro, J. Kandel, A.H. Hielscher, “Optical tomographic imaging of tumor hemodynamics during anit-VEGF treatment in mice,” Proceedings of the Biomedical Topical Meeting on Biomedical Optics – Optics in Cancer Research, Optical Society of America, Ft. Lauderdale, FL, March 19-22, 2006.
  76. D. Klose, A.H. Hielscher, “Fluorescence molecular tomography of small animals using the radiative transfer equation for curved geometries,” Proceedings of the Biomedical Topical Meeting on Biomedical Optics – Optics in Molecular Imaging and Drug Discovery, Optical Society of America, Ft. Lauderdale, FL, March 19-22, 2006.
  77. D. Klose, R. Song, A.K. Scheel, U. Netz , J. Beuthan , and A.H. Hielscher, “Three-Dimensional Image Reconstruction Of Human Finger Joints,” Proceedings of the Biomedical Topical Meeting on Biomedical Optics – Diffuse Optical Imaging, Optical Society of America, Ft. Lauderdale, FL, March 19-22, 2006.
  78. Gu, U. Netz, K. Ren, J. Beuthan, A.H. Hielscher, “Sensitivity analysis for frequency-domain optical tomography of small tissue volumes,” Proceedings of the Biomedical Topical Meeting on Biomedical Optics – Diffuse Optical Imaging, Optical Society of America, Ft. Lauderdale, FL, March 19-22, 2006.
  79. Ren, G. Bal, A.H. Hielscher, “Comparison of frequency-domain transport and diffusion-based reconstructions of small tissue volumes,” Proceedings of the Biomedical Topical Meeting on Biomedical Optics – Diffuse Optical Imaging, Optical Society of America, Ft. Lauderdale, FL, March 19-22, 2006.
  80. Lasker, D. Ginat, E. Dwyer, A.H. Hielscher, ”Comparison of static and dynamic optical tomographic imaging of rheumatoid joints,” Proceedings of the Biomedical Topical Meeting on Biomedical Optics – Diffuse Optical Imaging, Optical Society of America, Ft. Lauderdale, FL, March 19-22, 2006.
  81. D. Klose, A.H. Hielscher, “Functional imaging of small tissue volumes with diffuse optical tomography,” in Physiology, Function, and Structure from Medical Images, A. Amini, A. Manduca, eds., SPIE-International Symposium on Medical Imaging, Proc. 6143, #61431L (2006).
  82. M. Masciotti, F. Provenzano, J. Papa, A. Klose, J. Hur, X. Gu, D. Yamashiro M.D., J. Kandel M.D., A. H. Hielscher, “Monitoring tumor growth and treatment in small animals with magnetic resonance optical tomographic imaging,” in Multimodal Biomedical Imaging; Fred S. Azar, Dimitris N. Metaxas, eds., SPIE International Symposium on Biomedical Optics, Proc. SPIE 6081, #608105 (2006).
  83. D. Klose and A.H. Hielscher, “Image reconstruction algorithms based on the equation of radiative transfer,” Proceedings of the Numerical Heat Transfer Conference (Eurotherm 82), Cracow (Poland), 320-329, 2005.
  84. Y. Bluestone, Kenichi Sakamoto, A.H. Hielscher, M. Stewart, “Three-Dimensional Optical Tomographic Brain Imaging during Kainic-Acid-Induced Seizures in Rats,” in Physiology, Function, and Structure from Medical Images, A. Amini, A. Manduca, eds., SPIE-The International Society for Optical Engineering, Proc. 5746, pp. 58-66 (2005).
  85. Masciotti, G. Abdoulaev, J. Hur, J. Papa, J. Bae, J. Huang, D. Yamashiro, J. Kandel, A.H. Hielscher, “Combined optical tomographic and magnetic resonance imaging of tumor bearing mice,” in Optical Tomography and Spectroscopy of Tissue VI, B. Chance, R.R. Alfano, B.J. Tromberg, M. Tamura, E.M. Sevick-Muraca, eds., SPIE-The International Society for Optical Engineering, Proc. 5693, pp. 74-81 (2005).
  86. Ren, B. Moa-Anderson, G. Bal, X. Gu, A.H. Hielscher, “Frequency-domain tomography in small animals with the equation of radiative transfer,” in Optical Tomography and Spectroscopy of Tissue VI, B. Chance, R.R. Alfano, B.J. Tromberg, M. Tamura, E.M. Sevick-Muraca, eds., SPIE-The International Society for Optical Engineering, Proc. 5693, pp. 111-120 (2005).
  87. M. Lasker, E. Dwyer, A.H. Hielscher, “Optical tomographic imaging of vascular and metabolic reactivity in rheumatoid joints,” in Optical Tomography and Spectroscopy of Tissue VII, B. Chance, R.R. Alfano, B.J. Tromberg, M. Tamura, E.M. Sevick-Muraca, eds., SPIE-The International Society for Optical Engineering, Proc. 5693, pp. 406-416 (2005).
  88. Balasubramanyam, A.H. Hielscher, “Classification of optical tomographic joint images with support vector machines,” in Advanced Biomedical and Clinical Diagnostic Systems III, T. Vo-Dinh, W.S. Grundfest, eds., SPIE-The International Society for Optical Engineering, Proc. 5692, pp. 37-43 (2005).
  89. H. Hielscher, A.K. Scheel, A.D. Klose, B. Moa-Anderson, M. Backhaus, U. Netz, G.A. Müller, G.R. Burmester, and J. Beuthan, “Clinical Evaluation of an Optical Tomographic Finger Joint Imaging Systems,” Proceedings of the Biomedical Topical Meeting on Advances in Optical Imaging and Photon Migration, Optical Society of America, Miami Beach, FL, April 14-17, 2004.
  90. D. Klose, V. Ntziachristos, A.H. Hielscher, “Experimental validation of a fluorescence tomography algorithm based on the equation of radiative transfer,” Proceedings of the Biomedical Topical Meeting on Advances in Optical Imaging and Photon Migration, Optical Society of America, Miami Beach, FL, April 14-17, 2004.
  91. M. Lasker, J.Masciotti, M. Schoenecker, C. Schmitz, R.L. Barbour, A.H. Hielscher, “Prototype Digital Detection System for Optical Tomographic Imaging,” Proceedings of the Biomedical Topical Meeting on Advances in Optical Imaging and Photon Migration, Optical Society of America, Miami Beach, FL, April 14-17, 2004.
  92. Ren, G. Abdoulaev, G. Bal, A.H. Hielscher, “Modeling photon density wave propagation in turbid media with the equation of radiative transfer,” Proceedings of the Biomedical Topical Meeting on Advances in Optical Imaging and Photon Migration, Optical Society of America, Miami Beach, FL, April 14-17, 2004.
  93. H. Hielscher, A.D. Klose, A.K. Scheel, M. Backhaus, U.J. Netz, J. Beuthan, “Assessment of Finger Joint Inflammation by Diffuse Optical Tomography,” in Photon Migration and Diffuse Light Imaging, D. Boas, ed., SPIE-The International Society for Optical Engineering, Proc. 5138, pp. 46-54 (2003).
  94. H. Hielscher, G. Abdoulaev, A. Bluestone, J. Lasker, “Optical Tomographic Brain Imaging with Diffusion and Transport Theory Based Algorithms,” in Optical Tomography and Spectroscopy of Tissue V, B. Chance, R.R. Alfano, B.J. Tromberg, M. Tamura, E.M. Sevick-Muraca, eds., SPIE-The Intern. Society for Optical Engineering, Proc. 4955, pp. 12-21 (2003).
  95. Y. Bluestone, M. Stewart, J.M. Lasker, G.S. Abdoulaev, A.H. Hielscher, “Three-dimensional optical tomographic brain imaging during hypercapnia in rodents,” in Optical Tomography and Spectroscopy of Tissue V, B. Chance, R.R. Alfano, B.J. Tromberg, M. Tamura, E.M. Sevick-Muraca, eds., SPIE-The International Society for Optical Engineering, Proc. 4955, pp. 115-123 (2003).
  96. D. Klose, A.H. Hielscher, ” Optical fluorescence tomography with the equation of radiative transfer for molecular imaging,” in Optical Tomography and Spectroscopy of Tissue V, B. Chance, R.R. Alfano, B.J. Tromberg, M. Tamura, E.M. Sevick-Muraca, eds., SPIE-The International Society for Optical Engineering, Proc. 4955, pp. 219-225 (2003).
  97. D. Klose, A.H. Hielscher, “Modeling photon propagation in anisotropically scattering media with the equation of radiative transfer,” in Optical Tomography and Spectroscopy of Tissue V, B. Chance, R.R. Alfano, B.J. Tromberg, M. Tamura, E.M. Sevick-Muraca, eds., SPIE-The International Society for Optical Engineering, Proc. 4955, pp. 624-633 (2003).
  98. H. Hielscher, “Tomographic Imaging with Light,” 3rd International Conference on Advanced Optical Materials and Devices, August 19 – 22, 2002, Riga, Latvia.
  99. Bluestone, M. Stewart, J. M. Lasker, G.S. Abdoulaev, A.H. Hielscher, “Volumetric vascular brain imaging in small animals with near-infrared optical tomography,” 2002 IEEE Intern. Symposium on Biomedical Imaging: Macro to Nano, Washington, DC, July 7-10, 2002.
  100. H. Hielscher, G. Abdoulaev, A. Klose, A. Bluestone, J. Lasker, “Near-infrared optical imaging of fluid-containing tissues,” 2002 IEEE International Symposium on Biomedical Imaging: Macro to Nano, Washington, DC, July 7-10, 2002.
  101. H. Hielscher, A.D. Klose, U. Netz, H.J. Cappius, J. Beuthan, “Saggital optical tomography for the diagnosis of rheumatoid arthritis in finger joints,” in OSA Biomedical Topical Meetings, OSA Technical Digests, Optical Society of America, Washington, DC, 2002, pp. 590-592.
  102. D. Klose, A.H. Hielscher, “Optical tomographic image reconstruction with quasi-Newton methods,” in OSA Biomedical Topical Meetings, OSA Technical Digests, Optical Society of America, Washington, DC, 2002, pp. 131-133.
  103. S. Abdoulaev, A.H. Hielscher, “Optical tomographic image reconstruction with the three-dimensional equation of radiative transfer,” in OSA Biomedical Topical Meetings, OSA Technical Digests, Optical Society of America, Washington, DC, 2002, pp. 15-17.
  104. Bluestone, M. Stewart, J. M. Lasker, G.S. Abdoulaev, A.H. Hielscher, “Three dimensional optical tomographic brain imaging in small animals,” in OSA Biomedical Topical Meetings, OSA Technical Digests, Optical Society of America, Washington, DC, 2002, pp. 44-46.
  105. H. Hielscher, A. Bluestone, G.S. Abdoulaev, C.H. Schmitz, R. Barbour, “Volumetric imaging of hemodynamic effects in the human brain by three-dimensional diffuse optical tomography,” in OSA Biomedical Topical Meetings, OSA Technical Digests, Optical Society of America, Washington, DC, 2002, pp. 310-312.
  106. Lasker, A. Bluestone, C.H. Schmitz, R. Barbour, A.H. Hielscher, “Three-dimensional optical tomographic dynamic imaging of small tissue volumes,” in OSA Biomedical Topical Meetings, OSA Technical Digests, Optical Society of America, Washington, DC, 2002, pp. 524-526.
  107. H. Schmitz, H.L. Graber, R. Barbour, Y. Pei, J.M. Lasker, A.H. Hielscher, “A real time system for dynamic optical tomography,” in OSA Biomedical Topical Meetings, OSA Technical Digests, Optical Society of America, Washington, DC, 2002, pp. 181-183.
  108. H. Hielscher, M. Azeez-Jan, S. Bartel, “Tomographic Reconstruction of Layered Tissue Structures,” in Photon Migration, Optical Coherence Tomography, and Microscopy, S. Andersson-Engels, M.F. Kaschke, eds., SPIE-The International Society for Optical Engineering, Proc. 4431, pp. 126-133, 2001.
  109. H. Hielscher, A.Y. Bluestone, G.S. Abdoulaev, J. Lasker, R.L. Barbour, C.H. Schmitz, “Three Dimensional Tomographic Imaging of Vascular Reactivity in the Brain,” in Photon Migration, Optical Coherence Tomography, and Microscopy, S. Andersson-Engels, M.F. Kaschke, eds., SPIE-The International Society for Optical Engineering, Proc. 4431, pp. 207-218, 2001.
  110. H. Schmitz, Y. Pei, H.L. Graber, J.M. Lasker, A.H. Hielscher, R.L. Barbour, “Instrumentation for real-time dynamic optical tomography,” in Photon Migration, Optical Coherence Tomography, and Microscopy, S. Andersson-Engels, M.F. Kaschke, eds., SPIE-The International Society for Optical Engineering, Proc. 4431, pp. 282-291, 2001.
  111. Abdoulaev, A.H. Hielscher, “Inverse problem for the 3D equation of radiative transfer,” in Proceedings of 4TH European Conference Numerical Mathematics and Advanced Applications, Ischia, Italy, July 23-28, 2001(Springer-Verlag, Italy 2002)
  112. Abdoulaev, A. Klose, A. Bluestone, A.H. Hielscher, “Three-dimensional optical tomography based on the even-parity finite-element formulation of the radiative transfer equation,” in Optical Tomography and Spectroscopy of Tissue IV, B. Chance, R.R. Alfano, B.J. Tromberg, M. Tamura, and E.M. Sevick-Muraca, eds., SPIE-The International Society for Optical Engineering, Proc. 4250, pp. 53-60, 2001.
  113. Klose and A.H. Hielscher, “A hybrid approach for diffuse optical tomography combining evolution strategies and gradient techniques,” in Optical Tomography and Spectroscopy of Tissue IV, B. Chance, R.R. Alfano, B.J. Tromberg, M. Tamura, and E.M. Sevick-Muraca, eds., SPIE-The International Society for Optical Engineering, Proc. 4250, pp. 11-19, 2001.
  114. Bluestone, G. Abdoulaev, C. Schmitz, R.L. Barbour, A.H. Hielscher, “Three-dimensional optical-tomographic localization of changes in the absorption coefficients in the human brain ,” in Optical Tomography and Spectroscopy of Tissue IV, B. Chance, R.R. Alfano, B.J. Tromberg, M. Tamura, and E.M. Sevick-Muraca, eds., SPIE-The International Society for Optical Engineering, Proc. 4250, pp. 258-268, 2001.
  115. H. Schmitz, M. Löcker, J. Lasker, A.H. Hielscher, R.L. Barbour, “Performance characteristics of a silicon-photodiode-based instrument for fast functional optical tomography,” in Optical Tomography and Spectroscopy of Tissue IV, B. Chance, R.R. Alfano, B.J. Tromberg, M. Tamura, and E.M. Sevick-Muraca, eds., SPIE-The International Society for Optical Engineering, Proc. 4250, pp. 171-179, 2001.
  116. Beuthan, A.D. Klose, H. Cappius, U. Netz, A.H. Hielscher, “First investigation for the use of system theory in tissue optics,” in Optical Tomography and Spectroscopy of Tissue IV, B. Chance, R.R. Alfano, B.J. Tromberg, M. Tamura, and E.M. Sevick-Muraca, eds., SPIE-The International Society for Optical Engineering, Proc. 4250, pp. 1-10, 2001.
  117. H. Hielscher and A. Klose, “Evolution-theory-based algorithm for optical diffusion tomography,” in Photon Migration, Diffuse Spectroscopy, and Optical Coherence Tomography: Imaging and Functional Assessment, S. Andersson-Engels and J. Fujimoto, eds., SPIE-The International Society for Optical Engineering, Proc. 4160., pp. 118-127, 2000.
  118. H. Hielscher and S. Bartel, “Histogram derived penalty functions in gradient-based optical tomography,” Technical Digests: Biomedical Topical Meeting on Advances in Optical Imaging and Photon Migration, Optical Society of America, Miami Beach, FL, April 2-5, 2000, pp. 154-156.
  119. D. Klose, G. Abdoulaev, J. Beuthan and A.H. Hielscher, “Optical tomography with the equation of radiative transfer,” Technical Digests: Biomedical Topical Meeting on Advances in Optical Imaging and Photon Migration, Optical Society of America, Miami Beach, FL, April 2-5, 2000, pp. 342-344.
  120. Bartel and A.H. Hielscher, “Parallelization of gradient-based iterative image reconstruction scheme,” Technical Digests: Biomedical Topical Meeting on Advances in Optical Imaging and Photon Migration, Optical Soc. of America, Miami Beach, FL, April 2-5, 2000, pp. 433-435.
  121. D. Klose, A.H. Hielscher, and J. Beuthan, “Quasi-Newton methods in iterative image reconstruction schemes for optical tomography,” in Image Processing, K.M. Hanson, ed., SPIE-The International Society for Optical Engineering, Proc. 3979, pp. 1323-1330, 2000.
  122. A H. Hielscher and S. Bartel, “Overcoming iII-posedness in optical tomography,” in Image Processing, K.M. Hanson, ed., SPIE-The International Society for Optical Engineering, Proc. 3979, pp. 575-585, 2000.
  123. H. Hielscher and S. Bartel, “Diffuse backscattering Mueller matrix analysis for tissue diagnostics with polarized light,” in Optical Biopsy III, R.R. Alfano, ed., SPIE-The International Society for Optical Engineering, Proc. 3917, pp. 43-55, 2000.
  124. Bartel, A.D. Klose, A.H. Hielscher, “Anatomical Regularization Methods for Optical Tomography, Proceedings of The First Joint BMES/EMBS Conference – Serving Humanity Advancing Technology (21th Annual Conference of the IEEE Engineering in Medicine and Biology Society), Atlanta, GA, October 13 – 16, 1999, p. 1094.
  125. H. Hielscher and A.D. Klose, “Use of a priori information and penalty terms in gradient-based iterative reconstruction schemes,” in Optical Tomography and Spectroscopy of Tissue III, B. Chance, R.R. Alfano, B. Tromberg, eds., SPIE-The International Society for Optical Engineering, Proc. 3597, pp. 36-44, 1999.
  126. D. Klose and A. H. Hielscher, “A transport-theory based reconstruction algorithm for optical tomography,” in Optical Tomography and Spectroscopy of Tissue III, B. Chance, R.R. Alfano, B. Tromberg, eds., SPIE-The International Society for Optical Engineering, Proc. 3597, pp. 26-35, 1999.
  127. Vishnoi, A.H. Hielscher, N. Ramanujam, B. Chance, “Tissue phantom studies on photon migration through fetal brain in-utero using near infrared spectroscopy,” in Optical Tomography and Spectroscopy of Tissue III, B. Chance, R.R. Alfano, B. Tromberg, eds., SPIE-The International Society for Optical Engineering, Proc. 3597, pp. 650-660, 1999.
  128. H. Hielscher and A. Klose, “Image reconstruction schemes for optical tomography,” Proceedings 20th Annual Conference of the IEEE Engineering in Medicine and Biology Society, Hong Kong, China, October 29 – November 1, 1998, pp. 876-879.
  129. Klose, A.H. Hielscher, K.M. Hanson, J. Beuthan, “Three-dimensional optical tomography of a finger joint model for diagnostic of rheumatoid arthritis,” in Photon Propagation in Tissue IV, D.A. Benaron, M.D., B. Chance, M. Ferrari, M. Kohl, eds., SPIE-The International Society for Optical Engineering, Proc. 3566, pp. 151-160, 1998.
  130. H. Hielscher, A. Klose, D.M. Catarious Jr., K.M. Hanson, “Tomographic imaging of biological tissue by time-resolved, model-based, iterative, image reconstruction,” OSA Trends in Optics and Photonics: Advances in Optical Imaging and Photon Migration II, Vol. 21, R.R Alfano and J.G. Fujimoto, eds., Optical Society of America, Washington, DC, pp. 156-161, 1998.
  131. H. Hielscher, R.E. Alcouffe, “Discrete-ordinate transport simulations of light propagation in highly forward scattering media,” OSA Trends in Optics and Photonics: Advances in Optical Imaging and Photon Migration II, Vol. 21, R.R Alfano and J.G. Fujimoto, eds., Optical Society of America, Washington, DC, pp. 23-28, 1998.
  132. R. Mourant, A.H. Hielscher, J.P. Freyer, A.A. Eick, D.Shen, T.M. Johnson, “Scattering properties of biological cells,” OSA Trends in Optics and Photonics : Biomedical Optical Spectroscopy and Diagnostics II, Vol. 22, E. Sevick-Muraca and D. Benaron, eds., Optical Society of America, Washington, DC, pp. 11-15, 1998.
  133. H. Hielscher, A.A. Eick, J.R. Mourant, D. Chen, J.P. Freyer, I.J. Bigio, “Backscattering Mueller matrix analysis for biomedical optical diagnostics,” OSA Trends in Optics and Photonics: Biomedical Optical Spectroscopy and Diagnostics II, Vol. 22, E. Sevick-Muraca and D. Benaron, eds., Optical Society of America, Washington, DC, pp. 20-25, 1998.
  134. R. Mourant, A.H. Hielscher, A.A. Eick, J.P.Freyer, I.J. Bigio, “Cancer cell diagnostics with wavelength dependent and polarized light scattering,” R.R. Alfano, ed., SPIE-The International Society of Optical Engineering, Proc. 3250, pp. 26-32, 1998.
  135. H. Hielscher, ” Methods in photon migration tomography,” Proc. of the 19th Annual Conference of the IEEE Engineering in Medicine and Biology Society, Chicago, IL, October 30 – November 2, 1997, pp. 658-661.
  136. H. Hielscher, J.R. Mourant, I.J. Bigio, “Biomedical diagnostics with elastic light scattering in cell suspensions and tissues,” Proc. of the 19th Annual Conference of the IEEE Engineering in Medicine and Biology Society, Chicago, IL, Oct. 30 – Nov. 2, 1997, pp. 2716-2721.
  137. H. Hielscher, “Model-Based Iterative Image Reconstruction for Photon Migration Tomography,” in Methods for Solving Ill-Posed Inverse Imaging Problems: Medical and Nonmedical Applications, R.L. Barbour, M.J. Carvlin, and M.A. Fiddy, eds., SPIE-The International Society of Optical Engineering, Proc. 3171, pp. 106-117, 1997.
  138. H. Hielscher, A.A. Eick, J.R. Mourant, J.P.Freyer, I.J. Bigio, “Biomedical diagnostics with diffusely backscattered linearly and circularly polarized light,” in Biomedical Sensing, Imaging, and Tracking Technologies II, T. Vo-Dinh, R.A. Lieberman,and G.G. Vurek, eds., SPIE-The International Society of Optical Engineering , Proc. 2976, pp. 298-305, 1997.
  139. H. Hielscher, R.E. Alcouffe, R.L. Barbour, “Transport and diffusion calculations on MRI generated data”, in Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies, B. Chance and R.R. Alfano, eds., SPIE-The International Society for Optical Engineering, Proc. 2979, pp. 500-508, 1997.
  140. H. Hielscher, J.R. Mourant, I.J. Bigio, “Diffuse polarization spectroscopy on tissue phantoms and biological cell suspensions,” in Optical Biopsies and Microscopic Techniques, I.J. Bigio, W.S. Grundfest, K. Svanberg, H. Schneckenburger, and P.M. Viallet, eds., SPIE-The Internat. Soc. of Optical Engineering, Proc. 2926, pp. 67-76, 1996.
  141. H. Hielscher, R.E. Alcouffe, “Non-diffusive photon migration in homogeneous and heterogeneous tissues,” in Photon Propagation in Tissue II, B. Chance, D. Benaron, and G.J. Müller, eds., SPIE-The International Society of Optical Engineering, Proc. 2925, pp. 22-30, 1996.
  142. H. Hielscher, J.R. Mourant, I.J. Bigio, “Influence of particle size and concentration on diffuse backscattering of polarized light,” OSA Trends in Optics and Photonics: Biomedical Optical Spectroscopy and Diagnostics, E. Sevick-Muraca and D. Benaron, eds., Optical Society of America, Washington, DC, Vol. 3, pp. 26-31, 1996.
  143. H. Hielscher, K.M. Hanson, R.E. Alcouffe, J.S. George, “Comparison of discrete ordinate and diffusion theory calculations for photon migration in heterogeneous tissues,” OSA Trends in Optics and Photonics: Advances in Optical Imaging and Photon Migration, R.R Alfano and J.G. Fujimoto, eds., Optical Society of America, Washington, DC, Vol. 2, pp. 55-59, 1996.
  144. R. Mourant, A.H. Hielscher, D.M. Schmidt, J.S. George, “Broadband monitoring of physiological changes with a continuous light tissue spectrometer,” OSA Trends in Optics and Photonics: Biomedical Optical Spectroscopy and Diagnostics, E. Sevick-Muraca and D. Benaron, eds., Opt. Soc. of America, Washington, DC, Vol. 3, pp. 37-42, 1996.
  145. R. Mourant, A.H. Hielscher, “The significance of fiber numerical aperture for optical measurements of turbid media,” OSA Trends in Optics and Photonics on Biomedical Optical Spectroscopy and Diagnostics, E. Sevick-Muraca and D. Benaron, eds., Optical Society of America, Washington, DC, Vol. 3, pp. 32-36, 1996.
  146. R. Mourant, A.H. Hielscher, Irving J. Bigio, “Monte Carlo Simulations incorporating Mie calculations of light transport in tissue phantoms: Examination of photon sampling volumes for endoscopically compatible fiber optic probes,” in Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases III: Optical Biopsy, R.R. Alfano, ed., SPIE-The International Society of Optical Engineering , Proc. 2679, pp. 124-130, 1996.
  147. H. Hielscher, H. Liu, B. Chance, F.K. Tittel, S.L. Jacques, “Phase-resolved reflectance spectroscopy on layered turbid media,” in Optical Tomography, Photon Migration, and Spectroscopy of Tissues and Model Media: Theory, Human Studies, and Instrumentation, B. Chance and R.R. Alfano, eds., SPIE-The International Society of Optical Engineering, Proc. 2389, pp. 248-256, 1995.
  148. Liu, A.H. Hielscher, B. Chance, F.K. Tittel, S.L. Jacques, “Time-resolved photon migration in a heterogeneous tissue-vessel model,” in Optical Tomography, Photon Migration, and Spectroscopy of Tissues and Model Media: Theory, Human Studies, and Instrumentation, B. Chance and R.R. Alfano, eds., SPIE-The International Society of Optical Engineering, Proc. 2389, pp. 150-156, 1995.
  149. L. Jacques, A.H. Hielscher, “Discriminating shapes of objects within the tissue: frequency domain versus steady state measurements,” in Optical Tomography, Photon Migration, and Spectroscopy of Tissues and Model Media: Theory, Human Studies, and Instrumentation, B. Chance and R.R. Alfano, eds., SPIE-The International Society of Optical Engineering, Proc. 2389, pp. 228-239, 1995.
  150. H. Hielscher, S.L. Jacques, F.K. Tittel, “Imaging in biological tissues by means of diffraction tomography with photon density waves,” in Theoretical Study, Mathematical, Experimental Model for Photon Transport in Scattering Tissue, S. Avrillier, B. Chance and G.J. Müller, eds., SPIE-The Internat. Society of Optical Engineering, Proc. 2326, pp. 75-85, 1995.
  151. H. Hielscher, H. Liu, L.Wang , B. Chance, F.K. Tittel, S.L. Jacques, “Reflectance spectroscopy on layered tissues with strongly varying optical properties,” in Laser Interaction with Hard and Soft Tissue II, H.J. Albrecht, G.P. Delacretaz, T.H. Meier, R.W. Steiner, L.O. Svaasand and M.J.C. van Gemert, eds., SPIE-The International Society of Optical Engineering, Proc. 2323, pp. 351-359, 1995.
  152. R. Ostermeyer, A.H. Hielscher, L. Wang, S.L. Jacques, “Numerically modeling of light transport in inhomogenous tissues by superposition of virtual sources,” in Theoretical Study, Mathematical, Experimental Model for Photon Transport in Scattering Tissue, S. Avrillier, B. Chance and G.J. Müller, eds., SPIE-The International Society of Optical Engineering, Proc. 2326, pp. 56-64, 1995.
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  157. H. Hielscher, H. Liu, L.Wang , B. Chance, F.K. Tittel, S.L. Jacques, “Determination of blood oxygenation in the brain by time-resolved reflectance spectroscopy (I): Influence of the skin, skull and meniges,” in Biochemical Diagnostic Instrumentation A: Optical Diagnosis of Blood and Blood Components, R.F. Bonner, G.E. Cohn, T.M. Laue, A.V. Priezzhev, eds., SPIE-The International Society of Optical Engineering, Proc. 2136, pp. 4-15, 1994.
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  159. V. Stephens, L. Wang, A.H. Hielscher, F.K. Tittel, S. L. Jacques, “Detection of an object inside a phantom tissue using a spatial filter,” in Advances in Laser and Light Spectroscopy to Diagnose Cancer and other Diseases, R.R. Alfano, ed., SPIE-The Internat. Soc. of Optical Engineering, Proc. 2135, pp. 200-208, 1994.
  160. L. Jacques, M.R. Ostermeyer, L. Wang, A.H. Hielscher, “Light dosimetry in PDT using optical fiber delivery,” in Optical Methods for Tumor Treatment and detection: Mechanisms and Techniques in Photodynamic Therapy III, SPIE-The International Soc. of Optical Engineering, Proc. 2133, pp. 155-164, 1994.
  161. H. Hielscher, S.L. Jacques, F.K. Tittel, “Non invasive monitoring of blood oxygenation by phase resolved transmission spectroscopy,” in Photon Migration and Imaging in Random Media and Tissues, B. Chance and R.R. Alfano, eds., SPIE-The International Society of Optical Engineering, Proc. 1888, pp. 275-288, 1993.
  162. L. Jacques, A. H. Hielscher, L. Wang, F.K. Tittel, “How source/collector placement and subsurface absorbing layer affect time resolved and phase/modulation resolved photon migration,” in Photon Migration and Imaging in Random Media and Tissues, B. Chance and R.R. Alfano, eds., SPIE-The International Society of Optical Engineering, Proc. 1888, pp. 310-319, 1993.
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