Introduction: London has had frequent outbreaks of Escherichia coli (E. coli) in recent years. Between 2014 and 2018 England saw more than a 20% increase in E. coli cases. E. coli has become a risk to public health since it can cause death or lead to serious medical problems such as permanent kidney or brain damage, even after recovery from the infection. This Food Standards Agency Emergency Response Plan outlines the recommended procedures to effectively manage responses and mitigate risks during food safety emergencies like E. coli outbreaks.