Kirshenbaum Research Lab – NYU Chemistry

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Recently Published

  • Peptoid siRNA Delivery
    Peptoid siRNA Delivery

    Synthetic short interfering RNA (siRNA) oligonucleotides can trigger the RNA interference pathway and lead to selective gene silencing. Despite considerable enthusiasm and investme...

  • Peptoid-Protein Hybrids
    Peptoid-Protein Hybrids

    Chemical ligation protocols were explored for generating semisynthetic peptoid–protein hybrid architectures containing a native serine residue at the ligation site. Peptoid oligo...

  • Peptidomimetics in Rosetta
    Peptidomimetics in Rosetta

    Peptidomimetics are classes of molecules that mimic structural and functional attributes of polypeptides. Peptidomimetic oligomers can frequently be synthesized using efficient sol...


Synthesis

Peptoid-Protein Hybrids
Peptoid-Protein Hybrids

Chemical ligation protocols were explored for generating semisynthetic peptoid–protein hybrid architectures containing a native serine residue at the ligation site. Peptoid oligo...

More in Synthesis

Bioarchitectures

Multivalent Architectures
Multivalent Architectures

Multivalency is a powerful strategy in molecular pharmacology that can establish high-affinity binding between multiple conjoined ligands and corresponding biomolecular targets. Re...

More in Bioarchitectures

Biomedicine

Peptoid siRNA Delivery
Peptoid siRNA Delivery

Synthetic short interfering RNA (siRNA) oligonucleotides can trigger the RNA interference pathway and lead to selective gene silencing. Despite considerable enthusiasm and investme...

More in Biomedicine

Materials

Antifreeze Peptoids
Antifreeze Peptoids

The ability of natural peptides and proteins to influence the formation of inorganic crystalline materials has prompted the design of synthetic compounds for the regulation of crys...

More in Materials

Design

Peptidomimetics in Rosetta
Peptidomimetics in Rosetta

Peptidomimetics are classes of molecules that mimic structural and functional attributes of polypeptides. Peptidomimetic oligomers can frequently be synthesized using efficient sol...

More in Design