Chromosomes and Cancer

 

 

Welcome to JS Kang laboratory!!

Precise chromosome segregation is essential for the survival of eukaryotic cells and sophisticated mechanisms to orchestrate the mitotic machinery have been developed to guard the integrity of this process.  Since deregulation of this process leads to aneuploidy which is the common cause of birth defects and tumorigenesis, understanding the molecular mechanism of chromosome segregation is critical for the therapeutic intervention of these diseases.

Our lab is studying the fundamental questions of chromosome segregation and its deregulation in cancer.