
By Rick Valachovic, DMD, MPH, Clinical Professor and Co-Executive Director of the NYU Dentistry Center for Oral Health Policy and Management
U.S. dentists wrote almost nine million opioid prescriptions in 2022. I suspect the vast majority were written with only the best intentions for patients experiencing genuine pain. But given what we’ve learned about opioids, we need to ask: Were all of these prescriptions appropriate? Were patients put at risk?
I presume anyone reading this already knows that dentists have traditionally been the main prescribers of opioids to teenagers, typically in connection with third molar extractions. Studies show that young people who fill these prescriptions are at least twice and up to 14 times more likely to misuse opioids than their peers. The magnitude of this reality triggered research into alternatives for treating dental pain more than a decade ago, and the results were encouraging. Researchers found that ibuprofen and other non-steroidal anti-inflammatory drugs (NSAIDs), especially in combination with acetaminophen, were effective in treating post-operative dental pain without the adverse side effects — and risk of diversion, misuse, and overdose — associated with opioids.
Yet, data on commercially insured patients show that many dentists still routinely prescribe opioids following impacted third molar extractions, and 70% of patients fill those prescriptions. What’s going on?
A Security Blanket
“The opioid prescriptions are a security blanket,” says Cecile Feldman, DMD, professor and dean of the Rutgers University School of Dental Medicine. Even though most dentists now counsel their patients to take NSAIDs with acetaminophen first, old habits persist. “People feel more comfortable leaving with the prescription. Surgeons feel more comfortable giving them the prescription,” Cecile says. In her view, these just-in-case scripts send a subliminal message: “We don’t know if that non-opioid is going to work.”
Cecile led a team at Rutgers that studied the effectiveness of opioid vs. non-opioid analgesics for postoperative dental pain over the course of several days. They measured a range of patient-centered outcomes including side effects, sleep quality, and patients’ ability to resume normal activities without pain interference. The results? In addition to better sleep for the first night and less pain interference over the postoperative period, participants taking ibuprofen and acetaminophen also experienced fewer adverse effects with less severity.
Notably, the study participants taking non-opioid analgesics were half as likely as those taking an opioid with acetaminophen to need rescue medication. This finding should lay to rest a common concern that, without an opioid prescription, patients may call their dentists for pain medication at all hours of the night.
The Pace of Progress
A 2021 RAND Corporation study comparing the volume of dentist-prescribed opioid medicines dispensed by retail pharmacies in 2008-2009 with the volume dispensed in 2017-2018 found a substantial 41% drop. The researchers also found a dramatic 66% decrease in opioids dispensed to 18- to 25-year-olds. Contrast those findings with a 2013 survey of oral and maxillofacial surgeons, which found that all but two of 384 respondents routinely prescribed opioids after third molar extractions.
These declines represent meaningful progress, but the pace of that progress may have slackened. Researchers at the University of Michigan medical and dental schools analyzed the impact of the COVID-19 pandemic on U.S. dentists prescribing patterns. The researchers found that the number of opioid prescriptions rose during the first months of the pandemic, and the rate of decline subsequently slowed. As a result, the researchers calculated that 6.1 million more dental opioid prescriptions were dispensed in the 30 months ending in December 2022 than previous trends would have predicted.
“In the last 10 years, we’ve seen a decrease in prescribing narcotics postoperatively for dental pain, so we’re moving in the right direction,” says Paul Moore, DMD, PhD, MPH, professor emeritus at the University of Pittsburgh (Pitt) School of Dental Medicine. Paul led some of the research into the effectiveness of combining NSAIDs and acetaminophen for dental pain. More recently, he chaired a panel convened by Pitt, the American Dental Association, and the Center for Integrative Global Oral Health at the University of Pennsylvania (Penn) to create evidence-based clinical practice guidelines for the pharmacologic management of acute dental pain in children and in adolescents and adults. Those guidelines state unequivocally, “Clinicians should avoid the routine use of just-in-case prescribing of opioids and should exert extreme caution when prescribing opioids to adolescents and young adults.”
When Paul and I were dental students, the best option available was Tylenol with codeine. The advent of NSAIDs, which target inflammation, changed the game, he says. “They’re just particularly effective in treating dental pain, because dental pain is inflammatory to a great extent.” So why do some dentists still routinely prescribe opioids? Paul points to an age-old challenge. “It’s remarkable how slow it is to try to change practice habits,” he says.
Getting the Word Out
Deborah Polk, PhD, is a psychologist and visiting associate professor of dental public health in the School of Dental Medicine at Pitt. She is also co-principal investigator with Alonso Carrasco-Labra at Penn on the Food and Drug Administration grant that funded the guidelines’ development and dissemination.
Deb is leading that dissemination effort, which aims to inform dentists, emergency medical providers, and the public about the new standard of care in treating dental pain. Outreach to professional organizations and a wide array of media and social media outlets alerted millions to the new treatment guidelines. The effort yielded 430 news articles, almost 10,000 downloads of the guidelines in 2024, and a huge increase in visits to the ADA’s pain management webpages.
These results are impressive by any measure, but as Deb is quick to emphasize, “Knowledge alone doesn’t change behavior.” Implementing the guidelines also requires skills, opportunity, and motivation. One obstacle? “We heard that dentists didn’t know how to have the conversation about pain management with their patients,” Deb told me, so the team developed a one-page, visual conversation aid that dentists can use chairside. She and Paul also created an on-demand, free continuing education course that dentists can take to learn how to engage in shared decision-making with patients. A manuscript looking at the impact of the course on prescribing behaviors is currently in review.
Spurring Behavior Change
What more will it take to change the standard of care? Deb was part of a Pitt research team that looked at dentist prescribing trajectories from 2015-2019. They found that only 3.4% of dentists consistently prescribed opioids at high rates. “We thought, ‘Oh, they’re all oral and maxillofacial surgeons.’ No, 85% of them were general dentists,” she told me, which raised obvious concerns.
“Some of it is illegal, and state boards of dentistry need to be cracking down,” she says. As for other outliers, “Perhaps they trained in a time when we really thought that this pain was better managed by opioids. They think they’re doing the right thing, but now we know better,” she says.
Cecile’s group is also looking at patient and provider behaviors, the next front in the effort to stem inappropriate prescribing in our community. The Rutgers researchers hope to better understand how the practice environment influences what dentists prescribe. They also plan to ask, “Who goes and fills that prescription? If they fill it, do they take it?” Cecile told me.
I’m pleased to report that dental schools appear to be adhering to the new pain management guidelines. Paul told me that Pitt adopted a policy of no routine dispensing of opioids a decade ago. At Rutgers and here at NYU, students learn that opioids should only be dispensed as a last resort. Any dental school that needs help in updating its curriculum can turn to the Dental Education Core Competencies for the Prevention and Management of Prescription Drug Misuse prepared by the Commonwealth of Massachusetts in collaboration with the three Boston-based dental schools. Given these developments, I feel confident our graduates will prescribe non-opioid analgesics as the first-line therapy for dental pain in their practices. I hope ongoing and renewed efforts by researchers, professional associations, and regulatory bodies spur implementation of this updated standard of care by the entire practice community in the very near future.


By Rick Valachovic, DMD, MPH, Clinical Professor and Director of the NYU Dentistry Center for Oral Health Policy and Management

