Protease Inhibitor Adherence among Drug Users


This study followed 400 men for one year and examined how participants’ drug use/ abuse, experience with medication side effects, and life events affected adherence to highly active antiretroviral therapy (HAART) regimes containing protease inhibitors (PIs), as well as explored the sex and drug risk behaviors of study participants. The underlying purpose of the investigation was to help community agencies design and implement effective medication adherence interventions. The study recruited participants from gay venues, drug treatment programs, and AIDS service organizations using active and passive recruitment strategies.



Halkitis, P. N., Kutnick, A. H., Rosof. E., Slater, S., & Parsons, J. T. (2003). Adherence to HIV medications in a cohort of MSM: Impact of 9/11. Journal of Urban Health, 80(1), 161- 166.

Halkitis, P. N., Kutnick, A., & Slater, S. (2005). The social realities of adherence to protease inhibitor regimens: Substance use, health care, & psychological states. Journal of Health Psychology, 10(4), 545-558.

Halkitis, P.N., & Palamar, J. J. (2008). A mediation model to explain HIV Antiretroviral Adherence Among Gay and Bisexual Men. Journal of Gay & Lesbian Social Services, 19(1), 35-55.

Halkitis, P. N., Palamar, J. J., & Pandey Mukherjee, P. (2008). Analysis of HIV medication adherence in relation to person & treatment characteristics using hierarchical linear modeling. AIDS Patient Care & STDs, 22(4), 1-15.

Halkitis, P. N., Shrem, M., Zade, D., & Wilton, L. (2005). The physical, emotional, and interpersonal impact of HAART on the lives of seropositive individuals: Physical, psychological, and social realities. Journal of Health Psychology, 10(3), 345-358.

Solomon, T., & Halkitis P. N. (2008). Cognitive executive functioning in relation to HIV medication adherence among gay, bisexual, and other men who have sex with men. AIDS and Behavior, 12, 68-77.