Undergraduate star Kelvin Vuong is inducted to the Phi Lambda Upsilon National Chemistry Honors Society in recognition of his academic achievements.
Well deserved, Kelvin!
Author: Daniela Buccella
Veronika receives NSF GRFP Honorable Mention
Congratulations to graduate student Veronika Shchepetkina on being the recipient of an Honorable Mention in the highly competitive NSF Graduate Research Fellowship Program!
Restoring magnesium balance in the liver protects against drug-induced liver injury
Our study on cellular magnesium imbalance in drug induced liver injury is now in press (doi:10.1038/s41467-022-34262-0) in Nature Communications!
Acetaminophen overdose is one of the leading causes for acute liver failure. In this study, patients with acetaminophen-induced liver injury (AILI) were found to have abnormal serum magnesium levels and significantly elevated expression of Cyclin M4 (CNNM4), a protein that modulates cellular magnesium. Silencing of hepatic Cnnm4 in mice with acetaminophen overdose restored magnesium levels, ameliorating mitochondrial function and ER stress in affected hepatocytes. The study suggests a possible new therapeutic avenue for the treatment of AILI and further underscores the importance of magnesium balance in supporting liver health.
The research was conducted by an international team of scientists from Spain, Canada, Germany, and USA.
Commencement 2022
Finally coming together in person to celebrate three years of Buccella group graduates.
Very proud of you, Drs. Michael Brady (PhD ’21), Brismar Pinto-Pacheco (PhD ’20), and Elsy El Khoury (PhD ’22)!
Elsy defends her PhD thesis!
Elsy El Khoury defends her PhD thesis on molecular indicators for vibrational detection of cellular analytes.
Congratulations, Elsy!