Professor Arnold

Phone: 646.997.3899, (917) 568-6549

EMAIL: sa1577@nyu.edu

Office: Rogers Hall 620

RESEARCH INTERESTS

  • Microparticle Photophysics
  • Whispering Gallery Mode Biosensing
  • Organic Molecular Crystals

RECENT PUBLICATIONS

  • D. Keng, X. Tan, S. Arnold,”Whispering gallery micro-global positioning system for nanoparticle sizing in real time”, Appl. Phys. Lett. 105, 071105 (2014).
  • V.R. Dantham, S. Holler, C. Barbre, D. Keng, V. Kolchenko, S. Arnold,”Label-free Dectection of Single Protein using  a Nanoplasmonic-Photonic Hybrid Microcavity”, Nano Lett. 13, 3347-3351 (2013).
  • I.W. Selesnick, S. Arnold, V.R. Dantham, “Polynomial Smoothing of Time Series with Additive Step Discontinuities”, IEEE Trans. Signal Pross. 60, 6305-6318(2012).
  • S. Arnold, V.R. Dantham, C. Barbre, B.A. Garetz, “Periodic palsmonic enhancing epitopes on a whisperiong gallery mode biosensor”, Opt. Express 20, 26147-26159(2012).
  • V.R. Dantham, S. Holler, Z. Wan, V. Kolchenko, S. Arnold, “Taking Whispering Gallery Mode Single Virus Detection and Sizing to the Limit” , Appl. Phys. Lett. 101, 043704(2012).

Professor Barinov

Phone: 646.997.3661

Email: victor.barinov@nyu.edu

Office: Rogers Hall 640

RESEARCH INTERESTS

  • Adhesion of Electroactive Hydrogels
  • Electric Fields for Interface Separation and Cleaning
  • Electrospinning of Nanofibers
  • Polymer Mechanics

Professor Cowman

Phone: 212.992.5971

Email: mary.cowman@nyu.edu

Office: 433 First Avenue, Room 910

RESEARCH INTERESTS

  • Bioanalytical and buiphysical chemistry
  • Structure, function, and medical applications of the biomatrix surrounding cells, with special expertise in hyaluronan polysaccharide
  • Identification of biomarkers and bioactive fragments derived from extracellular matrix
  • Development of medical diagnostic assays
  • Discovery and devlopment of biotherapeutics and biomaterials

RECENT PUBLICATIONS

  • Cowman, M.K., Lee, H-G., Schwertfeger, K.L., McCarthy, J.B., and Turley, E.A. (2015) “The Content and Size of Hyaluronan in Biological Fluids and Tissues”, Frontiers in Immunology 6:261
  • Schwertfeger, K.L., Cowman, M.K., Telmer, P., Turley, E.A., and McCarthy, J.B. (2015) “Hyaluronan, Inflammation and Breast Cancer Progression,” Frontiers in Immunology 6:236
  • Yuan, H., Amin, R., Ye, X., de la Motte, C.A., and Cowman, M.K. (2015) “Determination of Hyaluronan Molecular Mass Distribution in Human Breast Milk” Anal. Biochem. 474, 78-88.
  • Ludwig, T., Cowman, M., Jay, G., Schmidt, T. (2014) “Effects of Concentration and Structure on Proteoglycan 4 Rheology and Interaction with Hyaluronan” Biorheology 51, 409-422.
  • Cowman, M.K., Lee, H-G., Schwertfeger, K.L., McCarthy, J.B., and Turley, E.A. (2015, in press) “The Content and Size of Hyaluronan in Biological Fluids and Tissues”, Frontiers in Immunology

 Professor Garetz

Phone: 646.997.3287

Email: bgaretz@nyu.edu

Office: Rogers Hall 801A

RESEARCH INTERESTS

  • Interaction of lasers with molecules and materials
  • Polarization effects and nonlinear optical effects
  • Laser spectroscopy
  • Laser light scattering
  • Ultrafast phenomena
  • Laser-induced nucleation

RECENT PUBLICATIONS

  • F.M. Abuzaina, B.A. Garetz, A.J. Patel, M.C. Newstein, S.P. Gido, X. Hu and N.P. Balsara, “Observation of Nematic Texture in a Diblock Copolymer Melt”, Macromolecules, in press, 2006.
  • X. Sun, B.A. Garetz and A.S. Myerson, “Supersaturation and Polarization Dependence of Nonphotochemical Laser-Induced Nucleation in Supersaturated Aqueous Glycine”, Cryst. Growth Des. in press, 2006.
  • J. Matic, X. Sun, B.A. Garetz and A.S. Myerson, “Intensity, Wavelength, and Polarization Dependence of Nonphotochemical Laser-Induced Nucleation in Supersaturated Aqueous Urea Solutions”, Cryst. Growth Des. 5, 1565 (2005).
  • F.M. Abuzaina, A.J. Patel, S. Mochrie, S. Narayanan, A.Sandy, B.A. Garetz, N.P. Balsara, “Structure and Phase Behavior of Block Copolymer Melts near the Sphere-Cylinder Boundary” Macromolecules 38, 7090 (2005).
  • B.A. Garetz, M.C. Newstein, J.D. Wilbur, A.J. Patel, D.A. Durkee, R. Segalman, J.A. Liddle, N.P. Balsara, “Grain Structure in Block Copolymer Thin Films Studied by Guided Wave Depolarized Light Scattering”, Macromolecules 38, 4282 (2005).
  • X. Hu, S.P. Gido, T.P. Russell, H. Iatrou, N. Hadjichristidis, F.M. Abuzaina, B.A. Garetz, “Grain Growth Kinetics of AnBn Star Block Copolymers in Supercritical Carbon Dioxide”, Macromolecules 38, 4719 (2005).

Professor Hartman

Phone: 646.997.3958

Email: ryan.hartman@nyu.edu

Office: Rogers Hall 600

RESEARCH INTERESTS

  • Catalysis and reaction engineering
  • Continuous-flow manufacturing
  • Flow chemistry
  • Microchemical systems
  • Molecular managemen

RECENT PUBLICATIONS

  • Hu, C., Garcia, N., Xu, R., Cao, T., Yen, A., Garner, S., Macias, J., Joshi, N., and Hartman, R.L. “Interfacial Properties of Asphaltenes at the Heptol-Brine Interface”, Energ. Fuel. (2015) accepted.
  • Hu, C., Yen, A., Joshi, N., and Hartman, R.L. “Packed-bed Microreactors for Understanding of the Dissolution Kinetics and Mechanisms of Asphaltenes in Xylenes”, Chem. Eng. Sci. (2015) accepted.
  • Hu, C., Shaughnessy, K.H., and Hartman, R.L. “Influence of water on the deprotonation and the ionic mechanisms of a Heck alkynylation and its resultant E-factors”, React. Chem. Eng. (2015) accepted.
  • Sabio, J.C., Domier, R.C., Moore, J.N., Shaughnessy, K., and Hartman, R.L. “Palladium theory of aqueous-phase Heck alkynylations for intensification of discovery and manufacture”,Chem. Eng. Technol., 38, 1717-1725 (2015).
  • Chen, Y., Sabio, J.C., and Hartman, R.L. “When solids stop flow chemistry in commercial tubing”,J. Flow Chem., 5(3), 166-171 (2015).

Professor Kim

Phone: 646.997.3719

Email: jin.kim@nyu.edu

Office: Rogers Hall 816B

RESEARCH INTERESTS

  • Protein engineering for therapeutic purpose
  • Protein folding and stability
  • Creation of protein-based biosensor
  • Design of an in situ molecular sensor for different aggregates species generated in Alzheimer’s and Parkinson’s disease
  • Characterization of protein aggregation
  • Development of mutation-free protein thermostabilization methods

 RECENT PUBLICATIONS

  • Brennal Pierre, Jason W. Labonte, Tina Xiong, Edwin Aoraha, Asher Williams, Vandan Shah, Edward Chau, Kazi Yasin Helal, Jeffrey Gray, Jin Ryoun Kim, “Molecular determinants for protein stabilization by insertional-fusion to a thermophilic host protein”, ChemBioChem, in press (2015)
  • Edwin Aoraha, Jason Candreva and Jin Ryoun Kim, “Engineering of a peptide probe for β-amyloid aggregates”, Molecular Biosystems, 11:2281-2289 (2015)
  • Brennal Pierre, Vandan Shah, Jenny Xiao and Jin Ryoun Kim, “Construction of a random circular permutation library using an engineered transposon”, Analytical Biochemistry, 474:16-24 (2015)
  • Keeshan Williams, Chung-Sei Kim, Jin Ryoun Kim and Rastislav Levicky, “Multimodal electrochemical sensing of transcription factor-operator complexes.”, Analyst, 139:1463-71 (2014)
  • Michael Hernandez, Yang Hu and Jin Ryoun Kim, “A conformation-switching fluoresent protein probe for detection of alpha synuclein oligomers”, Chemical Communications, 49:10712-4 (2013)

Professor Levicky

Phone: 646.997.3682

Email: rl306@nyu.edu

Office: Rogers Hall 816A

RESEARCH INTERESTS

  • Biointerfacial Engineering
  • Electrochemistry
  • Sensors and Biomolecular Diagnostics

RECENT PUBLICATIONS

  • Ping Gong, Kang Wang, Yatao Liu, Kenneth Shepard, Rastislav Levicky, “Molecular Mechanisms in Morpholino-DNA Surface Hybridization,” J. Am. Chem. Soc., 132, 9663-9671, (2010).
  • Damion Irving, Ping Gong, Rastislav Levicky, “DNA Surface Hybridization: Comparison of Theory and Experiment,” J. Phys. Chem. B, 114, 7631-7640, (2010).
  • Napoleon Tercero, Kang Wang, Ping Gong, Rastislav Levicky, “Morpholino Monolayers: Preparation and Label-free DNA Analysis by Surface Hybridization,” J. Am. Chem. Soc., 131, 4953-4961, (2009).
  • Kang Wang, Rebecca A. Zangmeister, Rastislav Levicky, “Equilibrium Electrostatics of Responsive Polyelectrolyte Monolayers,” J. Am. Chem. Soc., 131, 318-326, (2009).
  • Peter M Levine, Ping Gong, Rastislav Levicky, Kenneth L Shepard, “Real-time, Multiplexed Electrochemical DNA Detection Using an Active Complementary Metal-Oxide-Semiconductor Biosensor Array with Integrated Sensor Electronics,” Biosensors & Bioelectronics, 24, 1995-2001, (2009).

Professor Levon

Phone: 646.997.3339

Email: klevon@nyu.edu

Office: Rogers Hall 801A

RESEARCH INTERESTS

  • Phase separation in polymer blends and solutions, gelation, conductive polymers
  • Biosensors

RECENT PUBLICATIONS

  • Liquid Crystallinity in Electrically Conducting Polymers, Levon, K., Pashkovich, E., Park, K. C., accepted in “Electrical and Optical Polymer Systems”, Ed. G Wnek, D. Wise, Marcel Dekker, inc. New York, 5, 137-165 (1997).
  • Crystallization and Phase Separation of High-Density Polytehylene in the Presence of Comb-Like Polymer, Poly(Octadecylacrylate), Kim, M.S., Levon, K., European Polymer Journal, (1997)
  • Chromatic Changes in the Blends of Electroactive Polymers with Comb-Shaped Flexible Polymers, Kim, M.S., Levon, K., Macromol. Symp., 116, 73-104 (1997)
  • Order-Disorder Transition in Alkylated Polythiophenes, Park K.C., Levon, K., Macromolecules 30 (11) 3175-3183 (1997).
  • Blend of Electroactive Poly(3-dodecylthiophene) with Comb-like Alkylated Polyacrylate, Kim, M.S., Levon, K., J. Pol. Sci., Phys. Ed., 7, 1025-1041 (1997).

Professor Martucci

Phone: 646.997.3613

Email: cpm296@nyu.edu

Office: RH 701E

RESEARCH INTERESTS

 

RECENT PUBLICATIONS/WORK


Professor McDevitt

Phone: 212.998.9204

Email: mcdevitt@nyu.edu

Office: 433 First Avenue, Room 820

RESEARCH INTERESTS

Dr. John T. McDevitt is the Chair of the Biomaterials Department at New York University. He is also a member of both the NYU Bioengineering Institute and the NYU Department of Chemical and Biomolecular Engineering. McDevitt is a well-recognized national and international expert in the development of imaged-based biosensors. Over the past few years, he has served as the Principal Investigator for 6 major clinical trials and has a strong track record of translating essential bioscience discoveries into real-world clinical practice. His research team has developed a broad menu of tests spanning from general chemistry, protein, antibody, drug-metabolite, oligonucleotide, cell counting and cytology applications all using the same image-based approach.

RECENT PUBLICATIONS

  • 185. J.L. Ebersole, C. Campbell, John McDevitt, and C.S. Miller, “Serum and Salivary Analyte Levels and Oral Health in Metabolic Syndrome,” Journal of Periodontal Research, 2014, to be submitted.
  • 184. John T. McDevitt, “A Programmable Bio-Nano-Chip-based Point-of-Care Test for Measurement of Free, Complexed and Total Prostate Specific Antigen,” Clinica Chimica Acta, 2014, Submitted.
  • 183. McRae, M.P., Bozkurt, B., Ballantyne, C.M., Christodoulides, N., Simmons, G., Nambi, V., Miller, C.S., Ebersole, J.L., & McDevitt, J.T., “Cardiac ScoreCard: A Diagnostic Multivariate Index Assay System for Predicting Multiple Cardiovascular Disease Progression Levels,” Expert Systems with Applications, 2014, Submitted.
  • 182.  S. Speight, T. Abram, P. Floriano, R. James, M. Thornhill, K.R. Alexander, N. Vigneswaran, S. Redding, S. McGuff, C. Murdoch, J. Phelan, J.T. McDevitt, “Inter-observer Error in Dysplasia Grading: Towards an Enhanced Gold Standard for Clinical Pathology Trials,” Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2014, Submitted.
  • 181. G.W. Simmons, M. McRae, N. Christodoulides, J. Hayes, R. Mehalso, P. V. Ruijven and J.T. McDevitt, “Programmable Bio-Nano-Chip System: An Ultra-Flexible Platform for Bioscience and Clinical Measurements,” MicroTas2014, 2014, Submitted.

Professor Mijovic

Phone: 646.997.3097

Email: jovan.mijovic@nyu.edu

Office: Rogers Hall 728

RESEARCH INTERESTS

  • Molecular Motion and Relaxation in Synthetic and Biological Polymers
  • Dynamics of Glass Formers and Complex Fluids Nanocomposites in Electrical and Mechanical Fields

 RECENT PUBLICATIONS

  • 1. Lee, H.L.; Mijovic, J. “Bio-Nano Complexes: DNA/Surfactant/Single Walled Carbon Nanotube Interactions in Electric Field” Polymer 2009, 50, 881.
  • 2. Bian, Y.; Mijovic, J. “Effect of Side-Chain Architecture on Dielectric Relaxation in Polyhedral Oligomeric Silsesquioxane/Polypropylene Oxide Nanocomposites” Polymer 2009, 50, 1541.
  • 3. Ristic, S.; Mijovic, J. “Dynamics in Complex Systems: Dendrimer-Polymer Blends in Electric and Mechanical Fields” Polymer 2008, 49, 4695.
  • 4. Bian, Y.; Mijovic, J. “Nanonetworks of Multifunctional Polyhedral Oligomeric Polysilsesquioxane and Polypropylene Oxide” Macromolecules 2008, 41, 7122.
  • 5· Terenzi, A.; Vedova, C.; Lelli, G.; Mijovic, J.; Torre, L.; Valentini, L.; Kenny, J.M. “Chemorheological Behavior of Double-Walled Carbon Nanotube-Epoxy Nanocomposites” Composites Science and Technology 2008, 68, 1862.

Professor Montclare

Phone: 646.997.3679

Email: montclare@nyu.edu

Office: Rogers Hall 801C

RESEARCH INTERESTS

  • protein engineering
  • chemical biology
  • biomaterials self-assembly
  • artificial proteins biocatalyis

RECENT PUBLICATIONS

  • Min Dai,† Joseph A. Frezzo,† Etka Sharma, Raymond Chen, Navjot Singh, Carlo Yuvienco, Elif Caglar, Shu Xiao, Anjana Saxena & Jin K. Montclare (2016) Engineered Protein Polymer-Gold Nanoparticle Hybrid Materials for Small Molecule Delivery. J Nanomed Nanotechnol 7:356. doi:10.4172/2157-7439.1000356
  • Jasmin Hume, Raymond Chen, Rudy Jacquet, Michael Yang & Jin K. Montclare. Tunable Conformation Dependent Protein•Gold Nanoparticle Nanocomposites. Biomacromolecules (2015) 16, 1706-1713. DOI: 10.1021/acs.biomac.5b00098
  • Joseph A. Frezzo & Jin K. Montclare. Exploring the potential of engineered coiled-coil protein microfibers in drug delivery. Therapeutic Delivery (2015) 6, 643-646.
  • Haresh T. More, Kevin S. Zhang, Nikita Srivastiva, Joseph A. Frezzo & Jin K. Montclare. Influence of Fluorination on Protein Engineered Coiled-coil Fibers. Biomacromolecules (2015) 16, 1210–1217. DOI: 10.1021/bm5019062
  • Jasmin Hume, Jennifer Sun, Rudy Jacquet, P. Douglas Renfrew, Jesse A. Martin, Richard Bonneau, M. Lane Gilchrist & Jin K. Montclare. Engineered Coiled-Coil Protein Microfibers. Biomacromolecules (2014) 15, 3503-3510. DOI: 10.1021/bm5004948

Professor Pine

Phone: 646.997.3004

Email: pine@nyu.edu

Office: Rogers Hall 728

RESEARCH INTERESTS

  • Soft materials
  • Colloids
  • Emulsions
  • Self-assembly
  • Rheology

RECENT PUBLICATIONS

  • Dynamics of non-Brownian fiber suspensions under periodic shear. A Franceschini, E Filippidi, E Guazzelli and D J Pine, Soft Matter 10, 6722-6731 (2014).
  • A microscopic view of the yielding transition in concentrated emulsions.  E D Knowlton, D J Pine and L Cipelletti, Soft Matter 10, 6931-6940 (2014).
  • Shaping colloids for self-assembly. S Sacanna, M Korpics, K Rodriguez, L Colón-Meléndez, S-H Kim, D J Pine and G-R Yi, Nature Communications 4, 1688 (2013).
  • Living Crystals of Light-Activated Colloidal Surfers. J Palacci, S Sacanna, A S Steinberg, D J Pine and P M Chaikin, Science 339, 936–940 (2013).
  • Colloids with valence and specific directional bonding. Y Wang, Y Wang, D R Breed, V N Manoharan, L Feng, A D Hollingsworth, M Weck and D J Pine, Nature 491, 51–55 (2012).

Professor Teraoka

Phone: 646.997.3466

Email: teraoka@nyu.edu

Office: Rogers Hall 739B

RESEARCH INTERESTS

  • Photonic sensor
  • Whispering gallery mode

RECENT PUBLICATIONS


Professor Ulman

Phone: 646.997.3127

Email: au323@nyu.edu

Office: Rogers Hall 816

RESEARCH INTERESTS

  • Fundamental studies of self-assembled monolayers, surface engineering and interfacial phenomena including wetting, adhesion, and friction. Polymers at engineered interfaces.
  • Materials for nonlinear optics.
  • Nanoparticles.
  • Conducting Polymers.

RECENT PUBLICATIONS

  • Shaporenko, A.; Cyganik, P.; Buck, M.; Ulman, A. Zharnikov, M. Langmuir 2005, 21, 8204-8213. “Self-assembled monolayers of semifluorinated alkaneselenolates on noble metal substrates”
  • Tamam, L.; Kraack, H.; Sloutskin, E.; Ocko, B. M.; Pershan, P. S.; Ulman, A.; Deutsch, M. “Structure of Mercaptobiphenyl Monolayers on Mercury” J. Phys. Chem. B. 2005, 109, 12534-12543.
  • Spagnoli C.; Korniakov A.; Ulman A.; Balazs E. A; Lyubchenko Y. L; Cowman M. K Carbohydrate Res 2005, 340, 929-41. “Hyaluronan conformations on surfaces: effect of surface charge and hydrophobicity.
  • Stoycheva, S.; Himmelhaus, M.; Fick, J.; Kornviakov, A.; Grunze, M.; Ulman, A. Langmuir; 2006, 22, 4170-4178. “Spectroscopic Characterization of -Substituted Biphenylthiolates on Gold and Their Use as Substrates for “On-Top” Siloxane SAM Formation”
  • Xavier, J. H.; Sharma, S.; Seo, Y. S.; Isseroff, R.; Koga, T.; White, H.; Ulman, A.; Shin, K.; Satija, S. K.; Sokolov, J.; Rafailovich, M. H. Macromolecules 2006, 39, 2972-2980. “Effect of Nanoscopic Fillers on Dewetting Dynamics”

Current Projects Under BMS Lab

Professor  LeeProfessor Seidenstein


Summer Research Resources 2018:

Links for resources

3D Modelling of Muscles:

Participants:

Ms. Mackensie Gross

Purpose: CAD moodel and 3D print of skeletal muscle sarcomere, with binding sites to be used in an educational setting

Goals:

  1. Learn about 3D structure of a skeletal muscle and its components
  2. Determine dimensions of model to be made
  3. Start designing muscle with ability to contract
  4. Take a virtual tour of the 3D CAD world

Background Papers for students to read:

http://www.ncbi.nlm.nih.gov/books/NBK21724/

Please check the link: http://web.as.uky.edu/Biology/faculty/cooper/Education-Muscle/Module%202.htm


<Summer Undergraduate Research Program (SURP) 2nd Place>

blue ribbon

3D Modelling of Neuron:

Participants:

Ms. Kimberly Shaw 

Ms. Nadine Ibrahim

Ms. Changyong (Tina) Kim

Purpose: CAD Draw and 3D Model Multipolar Neuron and its ComponentsGoals:

  1. Learn about the 3D structure of neurons
  2. Determine dimensions of scaled model of neuron
  3. Start designing neurons with synapses that can interconnect
  4. Take a virtual tour of the 3D CAD world

Check Facebook
 
Background Papers for students to read:

http://3dprint.nih.gov/collections/neuroscience

Ascoli GA (2006) Mobilizing the base of neuroscience data: the case of neuronal morphologies. Nature Rev. Neurosci., 7:318-324

Carnevale, N.T. and Hines, M.L. The NEURON simulation environment in epilepsy research. In: Computational Neuroscience in Epilepsy, edited by I. Soltesz and K. Staley. London: Elsevier, 2008, pp. 18-33.

Hines ML, Morse T, Migliore M, Carnevale NT, Shepherd GM. ModelDB: A Database to Support Computational Neuroscience. J Comput Neurosci. 2004 Jul-Aug;17(1):7-11.

Jinseop S. Kim, Matthew J. Greene, Aleksandar Zlateski, Kisuk Lee, Mark Richardson, Srinivas C. Turaga, Michael Purcaro, Matthew Balkam, Amy Robinson, Bardia F. Behabadi, Michael Campos, Winfried Denk, H. Sebastian Seung  & the EyeWirers. Space–time wiring specificity supports direction selectivity in the retina. Nature. 509, 331–33. (15 May 2014). doi:10.1038/nature13240

McDougal RA and Shepherd GM (2015) 3D-printer visualization of neuron models. Front. Neuroinform. 9:18. doi: 10.3389/fninf.2015.00018

Migliore M, Morse TM, Davison AP, Marenco L, Shepherd GM, Hines ML. ModelDB: making models publicly accessible to support computational neuroscience. Neuroinformatics. 2003;1(1):135-9.


<SURP 2nd Place>

blue ribbon

3D Modelling of Bones:

Participants:

Ms. Kimberly Shaw

Purpose: 3D Model and print the Osteon and its substructures

Goals:

      1. Learn about 3D structure of bones
      2. Determine dimensions of bone to be modeled

 
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Chemtris (3D Tetris):

Participants:

Mr. MD Kabir

Purpose: Implement 3D molecular structures and understanding of rotation of chiral structures using a popular game platform

Goals:

    1. Help students understand how to rotate 3D objects to help them understand Chemisty and the world of chirality.
    2. Illustrate Hydrophobic and Hydrophilic 
    3. Illustrate how bonds work


              


The Staff of Gandalf:

Participants:

Ms. Francesca Santacroce

Mr. Hazena Ibrahim

Mr. Yohana Mpuya

Purpose: Produce a prototype of a 3D aware staff that allows the visually impaired to navigate.

Goals:

      1. Use of an infrared array to help the visually impaired user to visualize their surroundings
      2. Learn basics of arduino C and simple hardware wiring
      3. Learn to connect infrared sensor to tactile pins to correspond to what distance
      4. Learn to code arduino or other microcontrollers
      5. Test and debug code and design of staff prototype

   

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Background Papers for students to read:

https://www.arduino.cc/en/Reference/HomePage


Computational Modeling of Ischemia:

Participants:

Mr. Akash Das

Mr. Cvk Abhiroop

Ms. Jenny Ijoma

Ms. Amy Wu

Purpose: Techniques to discern Umbra vs. Penumbra, create working model with Extracellular(EC) space and Oxygen Glucose Deprivation (OGD)

Goals:

      1. Understand and Replicate the Schiff Model coded in virtual simulations
      2. Understand and Replicate the Hubel Model coded in virtual simulations
      3. Understand and Replcate the Grenier Model coded in virtual simulations

Check Instagram

Background Papers for students to read:

http://www.scholarpedia.org/article/Computer_modeling_of_ischemic_stroke

Grenier Papers : http://www.ncbi.nlm.nih.gov/pubmed/16368113  J Theor Biol. 2006 Jun 21;240(4):599-615. Epub 2005 Dec 20.A mathematical model of ion movements in grey matter during a stroke. Dronne MA1, Boissel JP, Grenier E

A global phenomenological model of ischemic stroke with stress on spreading depressions. Chapuisat G, Dronne MA, Grenier E, Hommel M, Gilquin H, Boissel JP. Prog Biophys Mol Biol. 2008 May;97(1):4-27. Epub 2007 Nov 1. Review.

Schiff Papers: J Neurophysiol. 2014 Jul 15; 112(2): 213–223.Oxygen and seizure dynamics: II. Computational modeling Yina Wei,Ghanim Ullah,Justin Ingram and  Steven J. Schiff

Hubel Papers: J Comput Neurosci. 2016 Apr;40(2):177-92. Large extracellular space leads to neuronal susceptibility to ischemic injury in a Na(+)/K (+) pumps-dependent manner. Hübel N1, Andrew RD2, Ullah G3.